Article
Unintended reporting of misleading Hb A(1c) values when using assays incapable of detecting hemoglobin variants.
Archives of pathology & laboratory medicine - 1 Dec 2013
Rhea Jeanne M, Koch David, Ritchie James, Singh Harsh V, Young Andrew N, Burgess Tom, Molinaro Ross J
Abstract excerpt
CONTEXT: It is recommended that hemoglobin (Hb) A1c (Hb A1c) not be used to assess average glycemia in patients who have altered red blood cell life span. OBJECTIVE: To investigate the frequency of reporting an Hb A1c value for Hb variant samples that do not include Hb A. DESIGN: Hb A1c samples (n = 500) were procured and screened for Hb variants that may affect Hb A1c interpretation (Hb SS, Hb SC, and Hb...
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