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A Rare Alpha Globin Chain Variant Hemoglobin Fontainebleau Poses Diagnostic Challenges by Yielding Different Results in Two Different HPLC Systems

2025-05-21

Abstract excerpt

<title>Abstract</title> <p>Alpha globin chain variants constitute a very small fraction of the total hemoglobinopathy cases. Their rarity and the often-unfamiliar elution times/patterns in high performance liquid chromatography (HPLC) that mimic those of normal hemoglobin (Hb) fractions and/or known beta globin variants, render their primary diagnosis difficult. We describe here Hb Fontainebleau, a rare alpha glo...

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Literature Corpus work
8f76caf9-2ab8-5ec9-9e0d-943eab1bd9f1
DOI
10.21203/rs.3.rs-6628570/v1
Open publication

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A Rare Alpha Globin Chain Variant Hemoglobin Fontainebleau Poses Diagnostic Challenges by Yielding Different Results in Two Different HPLC SystemsDOI 10.21203/rs.3.rs-6628570/v1
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