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Article

Evolution of Vertebrate Ryanodine Receptors Family in Relation to Functional Divergence and Conservation.

International heart journal - 12 Dec 2017

Ding Zhiwen, Peng Juan, Liang Yanyan, Yang Chunjie, Jiang Guoliang, Ren Jun, Zou Yunzeng

Abstract excerpt

Ryanodine receptors (RyRs), the large homotetrameric protein complexes, regulate the release of calcium from intracellular stores into the cytosol and play vital roles in the excitation-contraction coupling of cells. However, the evolutionary relationship of RyRs in vertebrates has yet to be elucidated. We identified 22 RyRs from Homo sapiens, Mus musculus, Rattus norvegicus, Gallus gallus, Anolis carolinensis,...

Topics

Animals
Chickens
Evolution, Molecular
Gene Ontology
Humans
Lizards
Mice
Mutation
Phylogeny
Rana catesbeiana
Rats
Ryanodine Receptor Calcium Release Channel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Selection, Genetic

Zebrafish

Source

Identifiers

PMID: 29151485
DOI: 10.1536/ihj.16-558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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