Article
β-Eudesmol, an oxygenized sesquiterpene, stimulates appetite via TRPA1 and the autonomic nervous system.
Scientific reports - 17 Nov 2017
Ohara Kazuaki, Fukuda Takafumi, Ishida Yuko, Takahashi Chika, Ohya Rena, Katayama Mikio, Uchida Kunitoshi, Tominaga Makoto, Nagai Katsuya
Abstract excerpt
Transient receptor potential ankyrin 1 (TRPA1) is a calcium-permeable non-selective cation channel, which is activated by various noxious or irritant substances in nature. TRPA1 activators have been generally recognized as noxious, however, foods and beverages containing TRPA1 activators are preferably consumed; the reasons for this discrepancy are not well understood. We demonstrate that TRPA1 is involved in the...
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