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Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults, a randomized, parallel arm, double-blind, placebo-controlled, pilot study

2024-05-05

Abstract excerpt

<h4>Objectives</h4> Ketone bodies are endogenous metabolites produced during fasting or a ketogenic diet that have pleiotropic effects on aging pathways. Ketone esters (KEs) are compounds that induce ketosis without dietary changes, but KEs have not been studied in an older adult population. The primary objective of this trial was to determine tolerability and safety of KE ingestion in older adults. <h4>Design</h4...

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Literature Corpus work
24cdc688-5d05-50da-a0a2-2ba4a9bfeaa8
DOI
10.1101/2024.05.03.24306699
Open publication

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Daily consumption of ketone ester, bis-octanoyl (R)-1,3-butanediol, is safe and tolerable in healthy older adults, a randomized, parallel arm, double-blind, placebo-controlled, pilot studyDOI 10.1101/2024.05.03.24306699
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