Article
Transient Receptor Potential (TRP) based polypharmacological combination stimulates energy expending phenotype to reverse HFD-induced obesity in mice.
Life sciences - 1 Jul 2023
Kaur Jasleen, Singh Dhirendra Pratap, Kumar Vijay, Kaur Simranjit, Bhunia Rupam Kumar, Kondepudi Kanthi Kiran, Kuhad Anurag, Bishnoi Mahendra
Abstract excerpt
BACKGROUND & AIM: Obesity is a worldwide epidemic leading to decreased quality of life, higher medical expenses and significant morbidity. Enhancing energy expenditure and substrate utilization in adipose tissues through dietary constituents and polypharmacological approaches is gaining importance for the prevention and therapeutics of obesity. An important factor in this regard is Transient Receptor Potential...
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