Article
KIR content genotypes associate with carriage of hepatitis B surface antigen, e antigen and HBV viral load in Gambians.
PloS one - 1 Jan 2017
Yindom Louis-Marie, Mendy Maimuna, Bodimeade Christopher, Chambion Caroline, Aka Peter, Whittle Hilton C, Rowland-Jones Sarah L, Walton Robert
Abstract excerpt
BACKGROUND: Hepatocellular carcinoma (HCC) causes over 800,000 deaths worldwide annually, mainly in low income countries, and incidence is rising rapidly in the developed world with the spread of hepatitis B (HBV) and C (HCV) viruses. Natural Killer (NK) cells protect against viral infections and tumours by killing abnormal cells recognised by Killer-cell Immunoglobulin-like Receptors (KIR). Thus genes and...
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