Article
GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.
Nature communications - 17 Nov 2017
Pirastu Nicola, Joshi Peter K, de Vries Paul S, Cornelis Marilyn C, McKeigue Paul M, Keum NaNa, Franceschini Nora, Colombo Marco, Giovannucci Edward L, Spiliopoulou Athina, Franke Lude, North Kari E, Kraft Peter, Morrison Alanna C, Esko Tõnu, Wilson James F
Abstract excerpt
Male pattern baldness (MPB) or androgenetic alopecia is one of the most common conditions affecting men, reaching a prevalence of ~50% by the age of 50; however, the known genes explain little of the heritability. Here, we present the results of a genome-wide association study including more than 70,000 men, identifying 71 independently replicated loci, of which 30 are novel. These loci explain 38% of the risk,...
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