Article
Genetic prediction of male pattern baldness.
PLoS genetics - 1 Feb 2017
Hagenaars Saskia P, Hill W David, Harris Sarah E, Ritchie Stuart J, Davies Gail, Liewald David C, Gale Catharine R, Porteous David J, Deary Ian J, Marioni Riccardo E
Abstract excerpt
Male pattern baldness can have substantial psychosocial effects, and it has been phenotypically linked to adverse health outcomes such as prostate cancer and cardiovascular disease. We explored the genetic architecture of the trait using data from over 52,000 male participants of UK Biobank, aged 40-69 years. We identified over 250 independent genetic loci associated with severe hair loss (P<5x10-8). By splitting...
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