Article
Pneumococcal surface protein A contributes to secondary Streptococcus pneumoniae infection after influenza virus infection.
The Journal of infectious diseases - 15 Aug 2009
King Quinton O, Lei Benfang, Harmsen Allen G
Abstract excerpt
We compared the growth of Streptococcus pneumoniae mutants with a disruption in the gene for either pneumococcal surface protein A (PspA-), neuraminidase A (NanA-), or hyaluronidase (Hyl-) to that of the parental strain D39 by means of a competitive growth model in mice with and those without prior influenza virus infection. The numbers of total bacteria recovered from mice with prior influenza virus infection...
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