Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of NP-Based Universal Vaccine for Influenza A Viruses

2 Feb 2024

Abstract excerpt

The nucleoprotein (NP) is a vital target for the heterosubtypic immunity of CD8+ cytotoxic T lymphocytes (CTLs) due to its conservation among influenza virus subtypes. To further enhance the T cell immunity of NP, autophagy-inducing peptide C5 (AIP-C5) from the CFP10 protein of Mycobacterium tuberculosis was used. Mice were immunized intranasally (i.n.) with human adenoviral vectors, HAd-C5-NP(H7N9) or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV Research and Treatment
Share to Influenza Virus Research Studies
Share to Vibrio bacteria research studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38400140
DOI: 10.3390/vaccines12020157

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of NP-Based Universal Vaccine for Influenza A VirusesPMID 38400140Read ↗

Influenza Virus-Derived CD8 T Cell Epitopes: Implications for the Development of Universal Influenza VaccinesSemantic proximity Read ↗

Non-neutralizing antibody responses to vesicular stomatitis virus-vectored influenza A virus vaccines correlate with protectionSemantic proximity Read ↗

Advances in Nanoparticle-Enhanced Vaccine Strategies: Towards a Universal Protection Against Influenza B VirusesSemantic proximity Read ↗

An mRNA-based broad-spectrum vaccine candidate confers cross-protection against heterosubtypic influenza A virusesSemantic proximity Read ↗

Adenoviral Vector-Based Vaccine Expressing Hemagglutinin Stem Region with Autophagy-Inducing Peptide Confers Cross-Protection Against Group 1 and 2 Influenza A VirusesSemantic proximity Read ↗

M2e-Based Influenza Vaccines with Nucleoprotein: A ReviewSemantic proximity Read ↗

Multi-Epitope Peptide-Based and Vaccinia-Based Universal Influenza Vaccine Candidates Subjected to Clinical TrialsSemantic proximity Read ↗

Development of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequenceSemantic proximity Read ↗

Mutant influenza A virus nucleoprotein is preferentially localized in the cytoplasm and its immunization in mice shows higher immunogenicity and cross-reactivity.Semantic proximity Read ↗

A/(H1N1) pdm09 NS1 promotes viral replication by enhancing autophagy through hijacking the IAV negative regulatory factor LRPPRCSemantic proximity Read ↗

Sequential Immunization with Universal Live Attenuated Influenza Vaccine Candidates Protects Ferrets against a High-Dose Heterologous Virus ChallengeSemantic proximity Read ↗

Protective Efficacy of the Conserved NP, PB1, and M1 Proteins as Immunogens in DNA- and Vaccinia Virus-Based Universal Influenza A Virus Vaccines in MiceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.