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Article

Successive influenza virus infection and Streptococcus pneumoniae stimulation alter human dendritic cell function.

BMC infectious diseases - 20 Jul 2011

Wu Yuet, Mao Huawei, Ling Man-To, Chow Kin-Hung, Ho Pak-Leung, Tu Wenwei, Lau Yu-Lung

Abstract excerpt

BACKGROUND: Influenza virus is a major cause of respiratory disease worldwide and Streptococcus pneumoniae infection associated with influenza often leads to severe complications. Dendritic cells are key antigen presenting cells but its role in such co-infection is unclear. METHODS: In this study, human monocyte derived-dentritic cells were either concurrently or successively challenged with the combination of...

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Identifiers

PMID: 21771345
DOI: 10.1186/1471-2334-11-201
PMCID: PMC3146832

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TNF

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