Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Atg9 antagonizes TOR signaling to regulate intestinal cell growth and epithelial homeostasis in Drosophila

9 Nov 2017

Abstract excerpt

Autophagy is essential for maintaining cellular homeostasis and survival under various stress conditions. Autophagy-related gene 9 (Atg9) encodes a multipass transmembrane protein thought to act as a membrane carrier for forming autophagosomes. However, the molecular regulation and physiological importance of Atg9 in animal development remain largely unclear. Here, we generated Atg9 null mutant flies and found...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Insect symbiosis and bacterial influences
Share to Invertebrate Immune Response Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29144896
DOI: 10.7554/elife.29338

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Atg9 antagonizes TOR signaling to regulate intestinal cell growth and epithelial homeostasis in DrosophilaPMID 29144896Read ↗

Role and regulation of starvation-induced autophagy in the Drosophila fat body.Semantic proximity Read ↗

The Genetics of Autophagy in Multicellular OrganismsSemantic proximity Read ↗

The C. elegans ATG101 homolog EPG-9 directly interacts with EPG-1/Atg13 and is essential for autophagy.Semantic proximity Read ↗

An Atg1/Atg13 complex with multiple roles in TOR-mediated autophagy regulation.Semantic proximity Read ↗

The early endosomal protein Rab21 is critical for enterocyte functions and intestinal homeostasisSemantic proximity Read ↗

ATG1, an autophagy regulator, inhibits cell growth by negatively regulating S6 kinase.Semantic proximity Read ↗

Eating on the fly: Function and regulation of autophagy during cell growth, survival and death in DrosophilaSemantic proximity Read ↗

The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development.Semantic proximity Read ↗

BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic traffickingSemantic proximity Read ↗

Using Drosophila melanogaster to Dissect the Roles of the mTOR Signaling Pathway in Cell GrowthSemantic proximity Read ↗

Dysfunctional peroxisomes compromise gut structure and host defense by increased cell death and Tor-dependent autophagySemantic proximity Read ↗

The autophagy-related gene Atg101 in Drosophila regulates both neuron and midgut homeostasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.