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Article

Integrative analysis of cyclin protein levels identifies cyclin b1 as a classifier and predictor of outcomes in breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2009

Agarwal Roshan, Gonzalez-Angulo Ana-Maria, Myhre Simen, Carey Mark, Lee Ju-Seog, Overgaard Jens, Alsner Jan, Stemke-Hale Katherine, Lluch Ana, Neve Richard M, Kuo Wen Lin, Sorlie Therese, Sahin Aysegul, Valero Vicente, Keyomarsi Khandan, Gray Joe W, Borresen-Dale Anne-Lise, Mills Gordon B, Hennessy Bryan T

Abstract excerpt

PURPOSE: We studied the expression levels of cyclins B1, D1, and E1 and the implications of cyclin overexpression for patient outcomes in distinct breast cancer subtypes defined by clinical variables and transcriptional profiling. EXPERIMENTAL DESIGN: The expression levels of cyclins B1, D1, and E1 were quantified in 779 breast tumors and 53 cell lines using reverse phase protein arrays and/or transcriptional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19470724
DOI: 10.1158/1078-0432.CCR-08-3293
PMCID: PMC2887710

Genes

AURKB
CCNB1
CENPE
CCNE1
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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