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Article

Alpha Carbonic Anhydrase from Nitratiruptor tergarcus Engineered for Increased Activity and Thermostability.

International journal of molecular sciences - 28 May 2024

Manyumwa Colleen Varaidzo, Zhang Chenxi, Jers Carsten, Mijakovic Ivan

Abstract excerpt

The development of carbon capture and storage technologies has resulted in a rising interest in the use of carbonic anhydrases (CAs) for CO2 fixation at elevated temperatures. In this study, we chose to rationally engineer the α-CA (NtCA) from the thermophilic bacterium Nitratiruptor tergarcus, which has been previously suggested to be thermostable by in silico studies. Using a combination of analyses with the...

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PMID: 38892041
DOI: 10.3390/ijms25115853
PMCID: PMC11173315

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