FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies.

doi:10.2337/db10-1340

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FTO, type 2 diabetes, and weight gain throughout adult life: a meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies.

Diabetes - 1 May 2011

Hertel Jens K, Johansson Stefan, Sonestedt Emily, Jonsson Anna, Lie Rolv T, Platou Carl G P, Nilsson Peter M, Rukh Gull, Midthjell Kristian, Hveem Kristian, Melander Olle, Groop Leif, Lyssenko Valeriya, Molven Anders, Orho-Melander Marju, Njølstad Pål R

Abstract excerpt

OBJECTIVE: FTO is the most important polygene identified for obesity. We aimed to investigate whether a variant in FTO affects type 2 diabetes risk entirely through its effect on BMI and how FTO influences BMI across adult life span. RESEARCH DESIGN AND METHODS: Through regression models, we assessed the relationship between the FTO single nucleotide polymorphisms rs9939609, type 2 diabetes, and BMI across life...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO

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PMID: 21398525
DOI: 10.2337/db10-1340
PMCID: PMC3292341

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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