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Article

Genetic prediction of type 2 diabetes using deep neural network.

Clinical genetics - 1 Apr 2018

Kim J, Kim J, Kwak M J, Bajaj M

Abstract excerpt

Type 2 diabetes (T2DM) has strong heritability but genetic models to explain heritability have been challenging. We tested deep neural network (DNN) to predict T2DM using the nested case-control study of Nurses' Health Study (3326 females, 45.6% T2DM) and Health Professionals Follow-up Study (2502 males, 46.5% T2DM). We selected 96, 214, 399, and 678 single-nucleotide polymorphism (SNPs) through Fisher's exact...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29136281
DOI: 10.1111/cge.13175

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