Article
Genetic Determinants of C1 Inhibitor Deficiency Angioedema Age of Onset.
International archives of allergy and immunology - 1 Jan 2017
Gianni Panagiota, Loules Gedeon, Zamanakou Maria, Kompoti Maria, Csuka Dorottya, Psarros Fotis, Magerl Markus, Moldovan Dimitru, Maurer Marcus, Speletas Matthaios G, Farkas Henriette, Germenis Anastasios E
Abstract excerpt
BACKGROUND: In view of the large heterogeneity in the clinical presentation of hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE), great efforts are being made towards detecting measurable biological determinants of disease severity that can help to improve the management of the disease. Considering the central role that plasma kallikrein plays in bradykinin production, we investigated the...
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