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Article

Leveraging Genetics for Hereditary Angioedema: A Road Map to Precision Medicine.

Clinical reviews in allergy & immunology - 1 Jun 2021

Germenis Anastasios E, Rijavec Matija, Veronez Camila Lopes

Abstract excerpt

Biochemical studies performed during the last decades resulted in the development of various innovative medicinal products for hereditary angioedema (HAE). These therapeutic agents target the production or the function of bradykinin-the main mediator of HAE due to C1-inhibitor (C1-INH) deficiency. However, despite these remarkable achievements, current knowledge cannot provide convincing explanations for the...

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Share to Angioedemas, Hereditary
Share to Autoimmune Bullous Skin Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bradykinin

Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema

Share to Complement C1 Inhibitor Protein

Share to Mast cells and histamine

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Share to Precision Medicine

Source

Identifiers

PMID: 33507496
DOI: 10.1007/s12016-021-08836-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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