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Article

Defining baseline epigenetic landscapes in the rat liver.

Epigenomics - 1 Dec 2017

Thomson John P, Ottaviano Raffaele, Buesen Roland, Moggs Jonathan G, Schwarz Michael, Meehan Richard R

Abstract excerpt

AIM: Characterization of the hepatic epigenome following exposure to chemicals and therapeutic drugs provides novel insights into toxicological and pharmacological mechanisms, however appreciation of genome-wide inter- and intra-strain baseline epigenetic variation, particularly in under-characterized species such as the rat is limited. Material & methods: To enhance the utility of epigenomic endpoints safety...

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Identifiers

PMID: 29130343
DOI: 10.2217/epi-2017-0029
PMCID: PMC5957268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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