Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sex and age differences in the expression of liver microRNAs during the life span of F344 rats

3 Feb 2017

Abstract excerpt

BACKGROUND: Physiological factors such as age and sex have been shown to be risk factors for adverse effects in the liver, including liver diseases and drug-induced liver injury. Previously, we have reported age- and sex-related significant differences in hepatic basal gene expression in rats during the life span that may be related to susceptibility to such adverse effects. However, the underlying mechanisms of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug-Induced Hepatotoxicity and Protection
Share to Liver physiology and pathology
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28174625
DOI: 10.1186/s13293-017-0127-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sex and age differences in the expression of liver microRNAs during the life span of F344 ratsPMID 28174625Read ↗

Age and sex differences in kidney microRNA expression during the life span of F344 ratsSemantic proximity Read ↗

Sex differences in kidney gene expression during the life cycle of F344 ratsSemantic proximity Read ↗

Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple TissuesSemantic proximity Read ↗

Early-Life Environmental Exposures Reprogram Epigenomic Aging to Alter Gene Expression TrajectoriesSemantic proximity Read ↗

Sex- and age-dependent gene expression in human liver: An implication for drug-metabolizing enzymesSemantic proximity Read ↗

Age-related Gene Expression Signatures (AGES) in rats demonstrate early, late, and linear transcriptional changes from multiple tissuesSemantic proximity Read ↗

Age‐Related Changes in MicroRNA Expression and Pharmacogenes in Human LiverSemantic proximity Read ↗

Defining baseline epigenetic landscapes in the rat liver.Semantic proximity Read ↗

Plasticity of Epigenomic and Transcriptomic Aging Reveals Common Targets for Reprogramming by Environmental ExposuresSemantic proximity Read ↗

Age-associated changes of cytochrome P450 and related phase-2 gene/proteins in livers of ratsSemantic proximity Read ↗

Sexual Dimorphism in the Expression of Mitochondria-Related Genes in Rat Heart at Different AgesSemantic proximity Read ↗

Delayed and Accelerated Aging Share Common Longevity Assurance MechanismsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.