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Article

Cost-effective and accurate method of measuring fetal fraction using SNP imputation.

Bioinformatics (Oxford, England) - 1 Apr 2018

Kim Minjeong, Kim Jai-Hoon, Kim Kangseok, Kim Sunshin

Abstract excerpt

Motivation: With the discovery of cell-free fetal DNA in maternal blood, the demand for non-invasive prenatal testing (NIPT) has been increasing. To obtain reliable NIPT results, it is important to accurately estimate the fetal fraction. In this study, we propose an accurate and cost-effective method for measuring fetal fractions using single-nucleotide polymorphisms (SNPs). Results: A total of 84 samples were...

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PMID: 29126132
DOI: 10.1093/bioinformatics/btx728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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