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Article

HOMINID: a framework for identifying associations between host genetic variation and microbiome composition.

GigaScience - 1 Dec 2017

Lynch Joshua, Tang Karen, Priya Sambhawa, Sands Joanna, Sands Margaret, Tang Evan, Mukherjee Sayan, Knights Dan, Blekhman Ran

Abstract excerpt

Recent studies have uncovered a strong effect of host genetic variation on the composition of host-associated microbiota. Here, we present HOMINID, a computational approach based on Lasso linear regression, that given host genetic variation and microbiome taxonomic composition data, identifies host single nucleotide polymorphisms (SNPs) that are correlated with microbial taxa abundances. Using simulated data, we...

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Identifiers

PMID: 29126115
DOI: 10.1093/gigascience/gix107
PMCID: PMC5740987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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