Article

HOMINID: A framework for identifying associations between host genetic variation and microbiome composition

2016-10-17

Abstract excerpt

Recent studies have uncovered a strong effect of host genetic variation on the composition of host-associated microbiota. Here, we present HOMINID, a computational approach based on Lasso linear regression, that given host genetic variation and microbiome composition data, identifies host SNPs that are correlated with microbial taxa abundances. Using simulated data we show that HOMINID has accuracy in identifying...

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Literature Corpus work: b429f661-8bec-5c2e-a3fb-2fd1462e04b3
DOI: 10.1101/081323

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