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Article

Testing in Microbiome-Profiling Studies with MiRKAT, the Microbiome Regression-Based Kernel Association Test.

American journal of human genetics - 7 May 2015

Zhao Ni, Chen Jun, Carroll Ian M, Ringel-Kulka Tamar, Epstein Michael P, Zhou Hua, Zhou Jin J, Ringel Yehuda, Li Hongzhe, Wu Michael C

Abstract excerpt

High-throughput sequencing technology has enabled population-based studies of the role of the human microbiome in disease etiology and exposure response. Distance-based analysis is a popular strategy for evaluating the overall association between microbiome diversity and outcome, wherein the phylogenetic distance between individuals' microbiome profiles is computed and tested for association via permutation....

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Identifiers

PMID: 25957468
DOI: 10.1016/j.ajhg.2015.04.003
PMCID: PMC4570290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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