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Article

Characterization of M1 and M2 polarization of macrophages in vascularized human dermo-epidermal skin substitutes in vivo.

Pediatric surgery international - 1 Feb 2018

Klar Agnes S, Michalak-Mićka Katarzyna, Biedermann Thomas, Simmen-Meuli Claudia, Reichmann Ernst, Meuli Martin

Abstract excerpt

AIMS AND OBJECTIVES: Vascularized bio-engineered human dermo-epidermal skin substitutes (vascDESS) hold promise for treating burn patients, including those with severe full-thickness wounds. We have previously shown that vascDESS promote wound healing by enhanced influx of macrophages and granulocytes. Immediately following transplantation, macrophages infiltrate the graft and differentiate into a...

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Source

Identifiers

PMID: 29124400
DOI: 10.1007/s00383-017-4179-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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