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Article

Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing.

International journal of molecular sciences - 17 Jul 2017

Hesketh Mark, Sahin Katherine B, West Zoe E, Murray Rachael Z

Abstract excerpt

Macrophages and inflammation play a beneficial role during wound repair with macrophages regulating a wide range of processes, such as removal of dead cells, debris and pathogens, through to extracellular matrix deposition re-vascularisation and wound re-epithelialisation. To perform this range of functions, these cells develop distinct phenotypes over the course of wound healing. They can present with a...

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Identifiers

PMID: 28714933
DOI: 10.3390/ijms18071545
PMCID: PMC5536033

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