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Article

Contribution of 3CD Region to the Virulence of Enterovirus 71.

Biomedical and environmental sciences : BES - 1 Oct 2017

Li Jing, Gao Feng, Hao Shu Bin, Cheng Dong, Zhang Wen Qiang, Lin Bin, Zhao Li, Yu Xue Jie, Wang Zhi Yu, Wen Hong Ling

Abstract excerpt

Enterovirus 71 is a neuroinvasive virus that is associated with severe neurological complications. We had earlier suggested that the replication capacity of a severe strain was higher than that of a mild strain. The recombinant 3CRV and 3CDRV virus strains were successfully rescued in our previous study. In the present study, we found no difference in virulence between 3CRV and severe strains. However, the...

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Identifiers

PMID: 29122098
DOI: 10.3967/bes2017.103

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