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Article

Gene polymorphisms of Interleukin 1? and Metalloproteinase 3 in Hepatitis C Infected Patients and Hepatocellular Carcinoma Patients.

The Egyptian journal of immunology - 1 Jan 2017

ElSheshtawy Nadia M, Nour Mona S, Hefny Zienab, Samir Ahmed

Abstract excerpt

Cytokines as IL 1? and matrix metalloproteinases (MMPs) are involved in tumor growth, invasion, and remote metastasis in various cancers. IL-1? ?31T/C polymorphism in the promoter region has been linked to an elevated risk of Hepatocellular carcinoma (HCC). MMP3 polymorphism at 1171 has also been linked to an elevated risk and a highly invasive type of HCC. Studying the association between IL-1? 31C/T gene...

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Identifiers

PMID: 29120572

Genes

MMP3

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