Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation in glia-neuron signalling modulates ageing rate.

Nature - 8 Nov 2017

Yin Jiang-An, Gao Ge, Liu Xi-Juan, Hao Zi-Qian, Li Kai, Kang Xin-Lei, Li Hong, Shan Yuan-Hong, Hu Wen-Li, Li Hai-Peng, Cai Shi-Qing

Abstract excerpt

The rate of behavioural decline in the ageing population is remarkably variable among individuals. Despite the considerable interest in studying natural variation in ageing rate to identify factors that control healthy ageing, no such factor has yet been found. Here we report a genetic basis for variation in ageing rates in Caenorhabditis elegans. We find that C. elegans isolates show diverse lifespan and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dopaminergic Neurons
Share to Locomotion
Share to Neuroglia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pharynx

Share to Receptors, G-Protein-Coupled

Share to Sexual Behavior, Animal

Share to Sirtuins

Share to Unfolded Protein Response

Source

Identifiers

PMID: 29120414
DOI: 10.1038/nature24463

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation in glia-neuron signalling modulates ageing rate.PMID 29120414Read ↗

Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans.Semantic proximity Read ↗

A recent global selective sweep on the age-1 phosphatidylinositol 3-OH kinase regulator of the insulin-like signaling pathway within Caenorhabditis remanei.Semantic proximity Read ↗

Neuronal aging: learning from C. elegansSemantic proximity Read ↗

Genetic variants that modify neuroendocrine gene expression and foraging behavior of C. elegans.Semantic proximity Read ↗

Genetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans.Semantic proximity Read ↗

Consolidating multiple evolutionary theories of ageing suggests a need for new approaches to study genetic contributions to ageing declineSemantic proximity Read ↗

Deep behavioural phenotyping reveals divergent trajectories of ageing and quantifies health state in <i>C. elegans</i>Semantic proximity Read ↗

Invertebrate gerontology: the age mutations of Caenorhabditis elegans.Semantic proximity Read ↗

Age-associated anatomical and physiological alterations in Caenorhabditis elegansSemantic proximity Read ↗

A role for worm <i>cutl-24</i> in background- and parent-of-origin-dependent ER stress resistanceSemantic proximity Read ↗

A role for worm cutl-24 in background- and parent-of-origin-dependent ER stress resistance.Semantic proximity Read ↗

Neuron-type specific aging-rate reveals age decelerating interventions preventing neurodegenerationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.