Article
Genetic variants that modify neuroendocrine gene expression and foraging behavior of C. elegans.
Science advances - 14 Jun 2024
Lee Harksun, Boor Sonia A, Hilbert Zoë A, Meisel Joshua D, Park Jaeseok, Wang Ye, McKeown Ryan, Fischer Sylvia E J, Andersen Erik C, Kim Dennis H
Abstract excerpt
The molecular mechanisms underlying diversity in animal behavior are not well understood. A major experimental challenge is determining the contribution of genetic variants that affect neuronal gene expression to differences in behavioral traits. In Caenorhabditis elegans, the neuroendocrine transforming growth factor-β ligand, DAF-7, regulates diverse behavioral responses to bacterial food and pathogens. The...
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