Article
Genetic architecture and regulatory impact on hepatic microRNA expression linked to immune and metabolic traits.
Open biology - 1 Nov 2017
Ponsuksili Siriluck, Trakooljul Nares, Hadlich Frieder, Haack Fiete, Murani Eduard, Wimmers Klaus
Abstract excerpt
Regulation of microRNA (miRNA) expression contributes to a wide range of target gene expression and phenotypes. The miRNA expression in the liver, the central metabolic organ, was examined in 209 pigs, and integrated with haematological and clinical biomarkers of metabolic and overall health, mRNA-target expression levels and single-nucleotide polymorphism (SNP) genotypes. The expression levels of 426 miRNA...
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