Article
Genetic dissection of blood lipid traits by integrating genome-wide association study and gene expression profiling in a porcine model.
BMC genomics - 3 Dec 2013
Chen Congying, Yang Bin, Zeng Zhijun, Yang Hui, Liu Chenlong, Ren Jun, Huang Lusheng
Abstract excerpt
BACKGROUND: Serum concentrations of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) are highly heritable traits that are used clinically to evaluate risk for cardiovascular disease in humans. In this study, we applied a genome-wide association study (GWAS) in 1,075 pigs from two populations and gene expression studies on 497...
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