Article
Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs.
Scientific reports - 19 Apr 2017
Ballester Maria, Ramayo-Caldas Yuliaxis, Revilla Manuel, Corominas Jordi, Castelló Anna, Estellé Jordi, Fernández Ana I, Folch Josep M
Abstract excerpt
In the present study, liver co-expression networks and expression Genome Wide Association Study (eGWAS) were performed to identify DNA variants and molecular pathways implicated in the functional regulatory mechanisms of meat quality traits in pigs. With this purpose, the liver mRNA expression of 44 candidates genes related with lipid metabolism was analysed in 111 Iberian x Landrace backcross animals. The eGWAS...
Topics
- Animals
- Female
- Gene Regulatory Networks
- Genome-Wide Association Study
- Lipid Metabolism
- Liver
- Male
- Polymorphism, Single Nucleotide
- Swine
