Article
IFNGR1 signaling is associated with adverse pregnancy outcomes during infection with malaria parasites.
PloS one - 1 Jan 2017
Niikura Mamoru, Inoue Shin-Ichi, Mineo Shoichiro, Asahi Hiroko, Kobayashi Fumie
Abstract excerpt
Complicated/severe cases of placental pathology due to Plasmodium falciparum and P. vivax, especially adverse pregnancy outcomes during P. vivax infection, have been increasing in recent years. However, the pathogenesis of placental pathology during severe malaria is poorly understood, while responses against IFN-γ are thought to be associated with adverse pregnancy outcomes. In the present study, we explored the...
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