Article
A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen.
The EMBO journal - 25 Feb 2004
Xu Hong, Lee Seung-Jae, Suzuki Emiko, Dugan Katherine D, Stoddard Alexander, Li Hong-Sheng, Chodosh Lewis A, Montell Craig
Abstract excerpt
The Drosophila visual system has provided a model to study phototransduction and retinal degeneration. To identify new candidate proteins that contribute to these processes, we conducted a genome-wide screen for genes expressed predominately in the eye, using DNA microarrays. This screen appeared to be comprehensive as it led to the identification of all 22 eye-enriched genes previously shown to function in...
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