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Article

Aberrant hypermethylation of the HOXD10 gene in papillary thyroid cancer with BRAFV600E mutation.

Oncology reports - 1 Jan 2018

Cao Yi-Ming, Gu Jun, Zhang Yan-Shu, Wei Wen-Jun, Qu Ning, Wen Duo, Liao Tian, Shi Rong-Liang, Zhang Ling, Ji Qing-Hai, Wang Yu, Sun Guo-Hua, Zhao Yang-Xing, Wang Yuan-Jin, Yu Jian, Zhu Yong-Xue

Abstract excerpt

Epigenetic abnormalities as well as genetic abnormalities may play a vital role in the tumorigenesis of papillary thyroid cancer (PTC). The present study aimed to analyze the function and methylation status of the HOXD10 gene in PTC and aimed to identify relationships between HOXD10 methylation, HOXD10 expression, BRAF mutation and clinicopathological characteristics of PTC. A total of 152 PTC patients were...

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Source

Identifiers

PMID: 29115628
DOI: 10.3892/or.2017.6058

Genes

HOXD10
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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