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To the end of the line: Axonal mRNA transport and local translation in health and neurodegenerative disease

8 Nov 2017

Abstract excerpt

Axons and growth cones, by their very nature far removed from the cell body, encounter unique environments and require distinct populations of proteins. It seems only natural, then, that they have developed mechanisms to locally synthesize a host of proteins required to perform their specialized functions. Acceptance of this ability has taken decades; however, there is now consensus that axons do indeed have the...

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PMID: 29115051
DOI: 10.1002/dneu.22555

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