Article

Altered mRNA transport and local translation in iNeurons with RNA binding protein knockdown

2024-09-27

Abstract excerpt

Neurons rely on mRNA transport and local translation to facilitate rapid protein synthesis in processes far from the cell body. These processes allow precise spatial and temporal control of translation and are mediated by RNA binding proteins (RBPs), including those known to be associated with neurodegenerative diseases. Here, we use proteomics, transcriptomics, and microscopy to investigate the impact of RBP knoc...

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Literature Corpus work: 1448c1c4-5270-5a7f-8e9e-443392784603
DOI: 10.1101/2024.09.26.615153

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