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Article

Identification of novel bone morphogenetic protein- responsive elements in a hepcidin promoter.

FEBS letters - 1 Dec 2017

Kanamori Yohei, Murakami Masaru, Matsui Tohru, Funaba Masayuki

Abstract excerpt

Hepcidin plays a central role in systemic iron metabolism. The bone morphogenetic protein (BMP) pathway regulates expression of hepcidin through transcriptional activation via BMP-responsive elements (REs) 1 and 2 on the promoter. Previous studies also revealed that the BMP pathway stimulates transcription of its target genes via GC-rich sequences on the promoter. A search for GC-rich sequences on the hepcidin...

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PMID: 29105755
DOI: 10.1002/1873-3468.12900

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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