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Article

Cannabinoid receptor 1/2 double-knockout mice develop epilepsy.

Epilepsia - 1 Dec 2017

Rowley Shane, Sun Xiaofei, Lima Isabel V, Tavenier Alexandra, de Oliveira Antonio Carlos Pinheiro, Dey Sudhansu K, Danzer Steve C

Abstract excerpt

The endocannabinoid system has gained attention as an important modulator of activity in the central nervous system. Initial studies focused on cannabinoid receptor 1 (CB1), which is widely expressed in the brain, but recent work also implicates cannabinoid receptor 2 (CB2) in modulating neuronal activity. Both receptors are capable of reducing neuronal activity, generating interest in cannabinoid receptor...

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Source

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Identifiers

PMID: 29105060
DOI: 10.1111/epi.13930
PMCID: PMC5716894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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