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Article

Genetic Manipulation of the Endocannabinoid System.

Handbook of experimental pharmacology - 1 Jan 2015

Zimmer Andreas

Abstract excerpt

The physiological and pathophysiological functions of the endocannabinoid system have been studied extensively using transgenic and targeted knockout mouse models. The first gene deletions of the cannabinoid CB(1) receptor were described in the late 1990s, soon followed by CB(2) and FAAH mutations in early 2000. These mouse models helped to elucidate the fundamental role of endocannabinoids as retrograde...

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Source

Identifiers

PMID: 26408160
DOI: 10.1007/978-3-319-20825-1_5

Genes

FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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