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Article

Is the Enzyme ACMSD a Novel Therapeutic Target in Parkinson's Disease?

Journal of Parkinson's disease - 1 Jan 2017

Thirtamara-Rajamani Keerthi, Li Peipei, Escobar Galvis Martha L, Labrie Viviane, Brundin Patrik, Brundin Lena

Abstract excerpt

Several large genome wide association studies have identified a locus in close proximity to the gene encoding the enzyme aminocarboxymuconate-semialdehyde-decarboxylase (ACMSD) to be associated with the risk for Parkinson's disease (PD), tentatively suggesting that this enzyme might influence PD pathogenesis. Further support for this comes from the recent identification of a disease-segregating stop codon...

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Identifiers

PMID: 29103054
DOI: 10.3233/JPD-171240
PMCID: PMC5676848

Genes

ACMSD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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