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Article

Differential ability of proinflammatory and anti-inflammatory macrophages to perform macropinocytosis.

Molecular biology of the cell - 1 Jan 2018

Redka Dar'ya S, Gütschow Michael, Grinstein Sergio, Canton Johnathan

Abstract excerpt

Macropinocytosis mediates the uptake of antigens and of nutrients that dictate the regulation of cell growth by mechanistic target of rapamycin complex 1 (mTORC1). Because these functions differ in proinflammatory and anti-inflammatory macrophages, we compared the macropinocytic ability of two extreme polarization states. We found that anti-inflammatory macrophages perform vigorous macropinocytosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29093026
DOI: 10.1091/mbc.E17-06-0419
PMCID: PMC5746066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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