Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alterations in the sperm histone-retained epigenome are associated with unexplained male factor infertility and poor blastocyst development in donor oocyte IVF cycles

3 Oct 2017

Abstract excerpt

STUDY QUESTION: Is there a distinct sperm histone-retained epigenetic signature in unexplained male factor infertility patients resulting in compromised blastocyst development? SUMMARY ANSWER: Using only donor oocyte IVF cycles, sperm DNA methylation patterns and miRNA profiles were significantly altered in normozoospermic patients resulting in poor blastocyst development, reflecting a subset of unexplained male...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Reproductive Biology and Fertility
Share to Reproductive Health and Technologies
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29087470
DOI: 10.1093/humrep/dex317

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alterations in the sperm histone-retained epigenome are associated with unexplained male factor infertility and poor blastocyst development in donor oocyte IVF cyclesPMID 29087470Read ↗

Could the sperm epigenome become a diagnostic tool for evaluation of the infertile man?Semantic proximity Read ↗

Broad <scp>DNA</scp> methylation changes of spermatogenesis, inflammation and immune response‐related genes in a subgroup of sperm samples for assisted reproductionSemantic proximity Read ↗

The human sperm epigenome and its potential role in embryonic developmentSemantic proximity Read ↗

Sperm chromatin: Evaluation, epigenetic signatures and relevance for embryo development and assisted reproductive technology outcomesSemantic proximity Read ↗

Differential sperm histone retention in normozoospermic ejaculates of infertile men negatively affects sperm functional competence and embryo qualitySemantic proximity Read ↗

Aberrant DNA methylation patterns of spermatozoa in men with unexplained infertilitySemantic proximity Read ↗

Sperm epigenetics in the study of male fertility, offspring health, and potential clinical applications.Semantic proximity Read ↗

Genome-wide differential methylation analyses identifies methylation signatures of male infertilitySemantic proximity Read ↗

Histone modification signatures in human sperm distinguish clinical abnormalitiesSemantic proximity Read ↗

Spermatozoa from infertile patients exhibit differences of DNA methylation associated with spermatogenesis-related processes: an array-based analysisSemantic proximity Read ↗

Integrated Analysis of DNA Methylation and mRNA Expression Profiles to Identify Key Genes in Severe OligozoospermiaSemantic proximity Read ↗

Altered histone retention and epigenetic modifications in the sperm of infertile menSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.