Article
Hydrogen Bond Variations of Influenza A Viruses During Adaptation in Human.
Scientific reports - 30 Oct 2017
Luo Jiejian, Deng Lizong, Ding Xiao, Quan Lijun, Wu Aiping, Jiang Taijiao
Abstract excerpt
Many host specific mutations have been detected in influenza A viruses (IAVs). However, their effects on hydrogen bond (H-bond) variations have rarely been investigated. In this study, 60 host specific sites were identified in the internal proteins of avian and human IAVs, 27 of which contained mutations with effects on H-bonds. Besides, 30 group specific sites were detected in HA and NA. Twenty-six of 36...
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