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Article

A novel non-canonical Wnt signature for prostate cancer aggressiveness.

Oncotarget - 7 Feb 2017

Sandsmark Elise, Hansen Ailin Falkmo, Selnæs Kirsten M, Bertilsson Helena, Bofin Anna M, Wright Alan J, Viset Trond, Richardsen Elin, Drabløs Finn, Bathen Tone F, Tessem May-Britt, Rye Morten B

Abstract excerpt

Activation of the Canonical Wnt pathway (CWP) has been linked to advanced and metastatic prostate cancer, whereas the Wnt5a-induced non-canonical Wnt pathway (NCWP) has been associated with both good and poor prognosis. A newly discovered NCWP, Wnt5/Fzd2, has been shown to induce epithelial-to-mesenchymal transition (EMT) in cancers, but has not been investigated in prostate cancer. The aim of this study was to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28030815
DOI: 10.18632/oncotarget.14161
PMCID: PMC5354754

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