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Article

Functional insight into the role of Orc6 in septin complex filament formation in Drosophila.

Molecular biology of the cell - 1 Jan 2015

Akhmetova Katarina, Balasov Maxim, Huijbregts Richard P H, Chesnokov Igor

Abstract excerpt

Septins belong to a family of polymerizing GTP-binding proteins that are important for cytokinesis and other processes that involve spatial organization of the cell cortex. We reconstituted a recombinant Drosophila septin complex and compared activities of the wild-type and several mutant septin complex variants both in vitro and in vivo. We show that Drosophila septin complex functions depend on the intact...

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Identifiers

PMID: 25355953
DOI: 10.1091/mbc.E14-02-0734
PMCID: PMC4279225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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