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Article

Axitinib attenuates intraplaque angiogenesis, haemorrhages and plaque destabilization in mice.

Vascular pharmacology - 1 Jan 2018

Van der Veken Bieke, De Meyer Guido R Y, Martinet Wim

Abstract excerpt

AIM: An increased density of intraplaque (IP) microvessels in ruptured versus nonruptured human plaques suggests that IP neovascularization has a major causative effect on plaque development and instability. Possibly, vascular endothelial growth factor (VEGF) or other angiogenic factors mediate IP microvessel growth and plaque destabilization. Because apolipoprotein deficient mice with a heterozygous mutation...

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Identifiers

PMID: 29079346
DOI: 10.1016/j.vph.2017.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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