Article
The presence of F cells with a fetal phenotype in adults with hemoglobinopathies limits the utility of flow cytometry for quantitation of fetomaternal hemorrhage.
Cytometry. Part B, Clinical cytometry - 1 Jul 2018
Othman Jad, Orellana Daniel, Chen Lin Selina, Russell Megan, Khoo Teh-Liane
Abstract excerpt
BACKGROUND: Detection and quantitation of fetomaternal hemorrhage (FMH) can be difficult in patients with pre-existing elevations of HbF, such as those with hemoglobinopathies. The aim of this study was to evaluate the utility of dual-color flow cytometry with the Fetal Cell Count Kit (FCCK) in differentiating adult and fetal HbF in this population, as compared to flow cytometry (FC) using HbF alone. METHODS:...
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